Wenjing Kang

MicroRNA Biology and Biogenesis: I develop computational methods to study microRNA genes, their biogenesis, and regulation. My work includes tools like MirGeneDB for comprehensive microRNA annotation and miRTrace for organismal origin detection in sequencing data. I also investigate how microRNA expression is tuned by structural stability and processing mechanisms.

Gene Regulation and Genome Organization: I study how gene expression is regulated at multiple levels, including transcription, RNA processing, and post-transcriptional regulation. My research explores the relationship between genome architecture, chromatin organization, and gene regulatory networks, with a focus on understanding cell type-specific mechanisms during development.

Computational RNA Biology: I develop bioinformatic frameworks and tools for analyzing diverse RNA sequencing datasets, including small RNA-seq, single-cell RNA-seq, and full-length capped RNA sequencing. My work aims to uncover patterns in RNA expression and processing that inform our understanding of biological systems and disease mechanisms.

Data Integration and Method Development: I work on integrating diverse biological datasets and developing computational methods that combine experimental data with computational predictions. This includes approaches for immune repertoire analysis, protein folding stress responses, and multi-omics data integration.